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Alignment of the holographic model and the real object in neuronavigation using augmented reality (AR): accuracy analysis of three methods

https://doi.org/10.64265/sibneuro-2025-1-1-26-36

Abstract

Introduction. Augmented reality (AR) technologies allow a surgeon to overlay three-dimensional virtual models onto real objects, enhancing visualization and facilitating the performance of complex surgeries. The primary objective of using AR in surgery is the precise alignment of the virtual model with the patient’s real anatomy, enabling the surgeon to see key anatomical structures as a projection onto or inside the body.

Materials and methods. The study utilized Microsoft Hololens 2 HMD (head-mounted display) glasses and the “Medgital” software for AR navigation. This article presents the results of a technical comparison of three methods for aligning AR 3D models with a patient’s head: alignment using craniometric points, the use of a QR code and a 3D printed frame and the application of pre-programmed points with a 3D pointer. The accuracy of fiducial point registration was assessed using the fiducial registration error (FRE) metric, and the execution time was measured for each method, allowing for the determination of their advantages and limitations.

Results. The mean FRE for alignment using craniometric points was 1.1 ± 0.3 cm, for the method using a QR code and a 3D printed frame it was 0.4 ± 0.3 cm, and for the method using pre-programmed points and a 3D pointer it was 0.7 ± 0.6 cm. The average alignment time was 180, 5, and 100 seconds, respectively. It was found that the method using the QR code and the 3D frame offered the highest accuracy, making it preferable for most clinical situations.

Conclusion. Each method has its own strengths and weaknesses; the choice depends on the clinical situation, available equipment, and required accuracy. The integration of AR technologies with surgical techniques improves the safety and precision of operative interventions.

About the Authors

A. N. Konovalov
N.N. Burdenko National Medical Research Center for Neurosurgery; I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
Russian Federation

Anton N. Konovalov – Cand. Sci. (Med.), Researcher, Neurosurgeon of the 3rd Neurosurgical Department (Vascular Neurosurgery), N.N. Burdenko National Medical Research Center for Neurosurgery; Senior Researcher of the Design Center for Flexible Bioelectronics, I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation

4-ya Tverskaya-Yamskaya str., 16, Moscow, 125047 

Trubetskaya str., 8, building 2, Moscow, 119991 



A. A. Artemyev
N.N. Burdenko National Medical Research Center for Neurosurgery
Russian Federation

Anton A. Artemyev – Clinical Resident 

4-ya Tverskaya-Yamskaya str., 16, Moscow, 125047 



D. N. Okishev
N.N. Burdenko National Medical Research Center for Neurosurgery
Russian Federation

Dmitry N. Okishev – Cand. Sci. (Med.), Researcher, Neurosurgeon of the 3rd Neurosurgical Department (Vascular Neurosurgery) 

4-ya Tverskaya-Yamskaya str., 16, Moscow, 125047 



Sh. Sh Eliava
N.N. Burdenko National Medical Research Center for Neurosurgery
Russian Federation

Shalva Sh. Eliava – Dr. Sci. (Med.), Professor, Corresponding Member of the Russian Academy of Sciences, Leading Researcher, Neurosurgeon, Head of the 3rd Neurosurgical Department (Vascular Neurosurgery) 

4-ya Tverskaya-Yamskaya str., 16, Moscow, 125047 



V. M Ivanov
Peter the Great St. Petersburg Polytechnic University
Russian Federation

Vladimir M. Ivanov – Dr. Sci. (Phys.-Math.), Cand. Sci. (Tech.), Professor of the Higher School of Theoretical Mechanics and Mathematical Physics 

Polytechnicheskaya str., 29, Saint Petersburg, 195251 



A. Yu. Smirnov
Peter the Great St. Petersburg Polytechnic University
Russian Federation

Anton Yu. Smirnov – Specialist of the Higher School of Theoretical Mechanics and Mathematical Physics 

Polytechnicheskaya str., 29, Saint Petersburg, 195251 



A. V. Knyazev
Natsstandart-distributsia LLC
Russian Federation

Alexander V. Knyazev – Head of the «Radiation Diagnostics» Department 

Vereyskaya str., 29, building 33, 3rd floor, room 5, Moscow, 121357 



S. V. Strelkov
Medzhital LLC
Russian Federation

Sergey V. Strelkov – Technical Director 

Lisichanskaya str., 6A, facility 14-n, room 2, Saint Petersburg, 197342 



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Review

For citations:


Konovalov A.N., Artemyev A.A., Okishev D.N., Eliava Sh.Sh., Ivanov V.M., Smirnov A.Yu., Knyazev A.V., Strelkov S.V. Alignment of the holographic model and the real object in neuronavigation using augmented reality (AR): accuracy analysis of three methods. Sibneuro. 2025;1(1):26-36. (In Russ.) https://doi.org/10.64265/sibneuro-2025-1-1-26-36

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ISSN 3033-649X (Print)
ISSN 3033-6805 (Online)