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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">sibneiro</journal-id><journal-title-group><journal-title xml:lang="ru">Сибнейро</journal-title><trans-title-group xml:lang="en"><trans-title>Sibneuro</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">3033-649X</issn><issn pub-type="epub">3033-6805</issn><publisher><publisher-name>Bervitskiy Anatoliy Vladimirovich</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.64265/3033-649X-2026.2.1.77-86</article-id><article-id custom-type="elpub" pub-id-type="custom">sibneiro-65</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Молодой ученый</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Young scientist</subject></subj-group></article-categories><title-group><article-title>Клинические случаи перфорации стенки средней мозговой артерии при тромбэкстракции у пациентов с острым ишемическим инсультом</article-title><trans-title-group xml:lang="en"><trans-title>Clinical cases of perforation of the wall of the middle cerebral artery during thrombextraction in patients with acute ischemic stroke</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4511-5774</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гаврилова</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Gavrilova</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гаврилова Анна Олеговна – клинический ординатор кафедры травматологии, ортопедии и нейрохирургии с курсом последипломного образования, ординатор</p><p>ул. Партизана Железняка, д. 1, г. Красноярск, 660022</p><p>ул. Партизана Железняка, д. 3А, г. Красноярск, 660022</p></bio><bio xml:lang="en"><p>Anna O. Gavrilova – Clinical Resident at the Department of Traumatology, Orthopedics and Neurosurgery with a Course of Postgraduate Education</p><p>Partizana Zheleznyaka str., 1, Krasnoyarsk, 660022</p><p>Partizana Zheleznyaka str., 3A, Krasnoyarsk, 660022</p></bio><email xlink:type="simple">anna-gavrilova20@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0630-7244</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Литвинюк</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Litvinyuk</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Литвинюк Никита Владимирович – ассистент кафедры лучевой диагностики с курсом последипломного образования; заведующий отделением рентгенохирургических методов диагностики и лечения</p><p>ул. Партизана Железняка, д. 1, г. Красноярск, 660022</p><p>ул. Партизана Железняка, д. 3А, г. Красноярск, 660022</p></bio><bio xml:lang="en"><p>Nikita V. Litvinyuk – Teaching Assistant at the Department of Radiodiagnostics with a Course of Postgraduate Education; Head of the Department of X-ray Surgical Methods of Diagnosis and Treatment</p><p>Partizana Zheleznyaka str., 1, Krasnoyarsk, 660022</p><p>Partizana Zheleznyaka str., 3A, Krasnoyarsk, 660022</p></bio><email xlink:type="simple">nikita.litvinyuk@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Красноярский государственный медицинский университет имени профессора В.Ф.Войно-Ясенецкого Минздрава России; Краевая клиническая больница<country>Россия</country></aff><aff xml:lang="en">Prof. V.F. Voino-Yasenetsky Krasnoyarsk State Medical University; Krasnoyarsk Regional Clinical Hospital<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>27</day><month>03</month><year>2026</year></pub-date><volume>2</volume><issue>1</issue><fpage>77</fpage><lpage>86</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гаврилова А.О., Литвинюк Н.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Гаврилова А.О., Литвинюк Н.В.</copyright-holder><copyright-holder xml:lang="en">Gavrilova A.O., Litvinyuk N.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.sibneurojournal.com/jour/article/view/65">https://www.sibneurojournal.com/jour/article/view/65</self-uri><abstract><sec><title>Введение</title><p>Введение. Эндоваскулярная тромбэкстракция является методом выбора при лечении ишемического инсульта, ассоциированного с тромбозом крупных церебральных артерий. По данным литературы, осложнения тромбэкстракции встречаются в 4–29  % случаев. Дистальная миграция тромбомасс, диссекция артерии, гематомы в области пункции бедренной артерии являются наиболее частыми осложнениями процедуры. Одним из редких, но серьезных осложнений является перфорация церебральной артерии во время тромбэкстракции, частота которой у разных исследователей колеблется от 0,6до9  %.</p></sec><sec><title>Описание случаев</title><p>Описание случаев. В данной работе описаны два клинических случая пациентов с ишемическим инсультом, у которых во время тромбэкстракции произошла перфорация средней мозговой артерии. Для остановки кровотечения в обоих случаях выполнена эмболизация средней мозговой артерии микроспиралями. Оба пациента выжили, несмотря на сформированные зоны ишемии. Одна пациентка выписана с функциональным исходом по модифицированной шкале Рэнкина на уровне Рэнкин 2, вторая пациентка – на уровне Рэнкин 4.</p></sec><sec><title>Обсуждение и заключение</title><p>Обсуждение и заключение. В нашей серии наблюдений частота перфорации церебральной артерии при тромбэкстракции составила 0,5  % (2из403случаев). В обоих случаях это были пожилые женщины (72и77лет). Факторов риска, как и причину развития перфорации средней мозговой артерии, выявить не удалось. При пересмотре сохранившихся ангиограмм и протоколов операции, технических погрешностей и трудностей входе вмешательства выявлено не было. Несмотря на возникшее катастрофическое осложнение, быстро выполненная эмболизация сосуда и последующая интенсивная терапия (борьба с отеком мозга, ангиоспазмом) позволили сохранить жизнь пациенткам и даже достичь удовлетворительного функционального статуса водном случае.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. Endovascular thrombextraction is the treatment of choice for ischemic stroke associated with thrombosis of large cerebral arteries. According to the literature, complications due to thrombextraction occur in 4–29 % of cases. Distal thrombus migration, arterial dissection, and hematomas at the femoral artery puncture site are the most common complications of the procedure. One rare but serious complication is cerebral artery perforation during thrombextraction, the incidence of which varies from 0.3 to 9 % according to different researchers.</p></sec><sec><title>Description of cases</title><p>Description of cases. This paper describes two clinical cases of patients with ischemic stroke in whom perforation of the middle cerebral artery occurred during thrombextraction. To stop bleeding in both cases, embolization and closure of the middle cerebral artery lumen with microcoils were performed. Both patients survived despite developing ischemic areas. One patient was discharged with a functional outcome according to the modified Rankin scale of Rankin 2, the second patient – Rankin 4.</p><p>Discussion and conclusion. In our series, the incidence of cerebral artery perforation during thrombextraction was 0.5 % (2 out of 403 cases). Both cases involved elderly women (72 and 77 years old). No risk factors or causes for middle cerebral artery perforation were identifi ed. A review of the surviving angiograms and surgical protocols revealed no technical errors or difficulties during the procedure. Despite the catastrophic complication, prompt embolization of the vessel and subsequent intensive care (control of cerebral edema and vasospasm) saved the patients’ lives and even achieved satisfactory functional status in one case.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>перфорация артерии</kwd><kwd>тромбэкстракция</kwd><kwd>острый ишемический инсульт</kwd><kwd>средняя мозговая артерия</kwd><kwd>осложнение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>arterial perforation</kwd><kwd>thrombextraction</kwd><kwd>acute ischemic stroke</kwd><kwd>middle cerebral artery</kwd><kwd>complication</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Feigin VL, Brainin M, Norrving B, Martins SO, Pandian J, Lindsay P, et al. World Stroke Organization: Global stroke fact sheet 2025. 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